Evidence Synthesis Center Amsterdam (ESCA)
Advancing the methods and practice of evidence synthesis
Research and expertise at ESCA
We develop, evaluate, and apply methods for evidence synthesis to promote rigorous, transparent, and reproducible approaches to synthesizing research evidence and informing healthcare, research, and decision-making. We support researchers and healthcare professionals through methodological consultation, training, resources, and collaborative evidence synthesis.
Resources

Types of Synthesis
An overview of the most important methodological types of evidence synthesis

Systematic Review
At ESCA, we design and conduct systematic reviews and enable others to do the same


Artificial Intelligence (AI) Methods
How ESCA applies AI in evidence synthesis, the opportunities it offers, and the challenges it presents

Guideline Development
How to translate evidence into practical recommendations to support clinical, public health, or policy decision-making


EDS
Epidemiology and Data Science (EDS) Consult offers methodological and statistical consultancy on the design, analysis and reporting of scientific research at Amsterdam UMC

Library
Amsterdam UMC Libraries provide support for developing and executing search strategies, as well as delivering search results to Amsterdam UMC researchers
Services
We conduct independent and commissioned research. To initiate a commissioned review, please contact us.
Clinical Epidemiology: Systematic Reviews (AMC PhD Program)
Evidence for Planet
We believe evidence is essential not only for better health, but also for a more sustainable future.
Whether through evaluating sustainable interventions, identifying knowledge gaps, or promoting environmentally responsible research practices, ESCA brings together expertise, collaboration, and integrity to build the evidence base our planet needs.
We are committed to advancing evidence that promotes sustainability in healthcare, policy, and research. Within ESCA, we also turn the lens inward—examining how evidence is produced, communicated, and applied, to make research practices more transparent, efficient, and environmentally conscious.
Our experts at ESCA actively contribute to this mission within Amsterdam UMC and in partnership with other research groups across the Netherlands. A key principle we uphold is reducing research waste: by mapping what is already known, we help avoid unnecessary duplication, guide more efficient study designs, and ensure that research efforts are focused where they are most needed.
The outputs of our ongoing and completed projects will be shared here soon.
