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Evidence Synthesis Center Amsterdam (ESCA)

Evidence makes it possible

We enable researchers and healthcare professionals setting up and conduct evidence syntheses through training, tailored resources, expert consultation, and services. We produce systematic reviews to help making informed decisions in health and medical research

Based in the Department of Epidemiology and Data Science at Amsterdam UMC, we collaborate with clinicians and other researchers across disciplines, and institutions

Resources

RESOURCES

An overview of the most important methodological types of evidence synthesis

RESOURCES

At ESCA, we design and conduct systematic reviews and enable others to do the same

RESOURCES

An outline and guide to the key components of conducting a meta-analysis

RESOURCES

How ESCA applies AI in evidence synthesis, the opportunities it offers, and the challenges it presents

RESOURCES

A guidance on how to use GRADE for your evidence synthesis

RESOURCES

How to translate evidence into practical recommendations to support clinical, public health, or policy decision-making

RESOURCES

A hands-on guide on how to conduct a systematic review

Consult

for Amsterdam UMC researchers.

EDS

Consult

Epidemiology and Data Science (EDS) Consult offers methodological and statistical consultancy on the design, analysis and reporting of scientific research at Amsterdam UMC

Library

Consult

Amsterdam UMC Libraries provide support for developing and executing search strategies, as well as delivering search results to Amsterdam UMC researchers

Services

We conduct independent and commissioned research. To initiate a commissioned review, please contact us.

Courses

For Amsterdam UMC Researchers and Open Courses for All

Systematische reviews en meta-analyse (EpidM master)

Clinical Epidemiology: Systematic Reviews (AMC PhD Program)

Evidence for Planet

We believe evidence is essential not only for better health, but also for a more sustainable future.

The climate crisis is among the greatest challenges of our time, and evidence has a critical role to play in addressing it.

Whether through evaluating sustainable interventions, identifying knowledge gaps, or promoting environmentally responsible research practices, ESCA brings together expertise, collaboration, and integrity to build the evidence base our planet needs.

🌱 How ESCA Supports Sustainability

We are committed to advancing evidence that promotes sustainability in healthcare, policy, and research. Within ESCA, we also turn the lens inward—examining how evidence is produced, communicated, and applied, to make research practices more transparent, efficient, and environmentally conscious.

Our experts at ESCA actively contribute to this mission within Amsterdam UMC and in partnership with other research groups across the Netherlands. A key principle we uphold is reducing research waste: by mapping what is already known, we help avoid unnecessary duplication, guide more efficient study designs, and ensure that research efforts are focused where they are most needed.

The outputs of our ongoing and completed projects will be shared here soon.

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